What is Familial Mediterranean Fever?

Familial Mediterranean Fever (FMF) is a genetic disorder that causes recurrent, painful inflammatory attacks in the chest, abdomen, or joints. FMF is typically seen in people of Mediterranean descent and follows an autosomal recessive inheritance pattern, meaning it occurs when both parents carry the mutated gene. The disease is caused by a mutation in the MEFV gene, which affects the normal function of this gene.

Symptoms of Familial Mediterranean Fever include:

Abdominal Pain: Severe pain in the abdominal region is a typical symptom of FMF. These pains occur in episodes.

Recurrent Fever Episodes: FMF is characterized by fever spikes. During attacks, body temperature rises, and these episodes are usually short-lived but intense.

Chest Pain That Makes Breathing Difficult: Pain in the chest area and difficulty breathing are among the symptoms of the disease. This condition is often associated with inflammation of the pleural membranes.

Skin Rashes: During attacks, redness and rashes may appear on the skin, particularly on the legs and below the knees.

Joint Swelling: Swelling in the knees, ankles, and hip joints is among the areas affected by the disease.

Muscle Pain: Muscle aches may also occur during attacks.

Swelling and Tenderness in the Scrotum: In men, swelling and pain in the scrotum may occur.

There is no complete cure for Familial Mediterranean Fever, but the symptoms caused by the disease can be managed. Patients are generally prescribed painkillers, anti-inflammatory drugs, and medications such as colchicine. Treatment plans for patients are determined based on the severity and frequency of the symptoms.

News Source: 12punto